This is probably the first mention of the Holland Tunnel in comics. Using familiar landmarks is a good way to reinforce the idea that the Heroes are in a real place that exists.
Although I was initially New York ignorant enough to think that Pennsylvania Station would be in Pennsylvania, I learned that this is still another NYC location. This "Washington Special", then, would have been the fastest way from New York to Washington, D.C., short of taking a plane.
(Scans courtesy of Digital Comic Museum)